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Antibodies

Bcl-2 Antibody

Product Sizes
0.1 mg
£409.00
OASB01185-0.1MG
About this Product
SKU:
OASB01185
Additional Names:
Bcl-; Bcl-2; AW986256; C430015F12Rik; D630044D05Rik; D830018M01Rik
translate.label.attr.clone:
10C4
Clonality:
Monoclonal
Conjugate:
Unconjugated
Concentration:
0.1 mg/mL
Extra Details:
This gene encodes a member of the B cell lymphoma 2 protein family. Members of this family regulate cell death in multiple cell types and can have either proapoptotic or antiapoptotic activities. The protein encoded by this gene inhibits mitochondrial-mediated apoptosis. This protein is an integral outer mitochondrial membrane protein that functions as part of signaling pathway that controls mitochondrial permeability in response to apoptotic stimuli. This protein may also play a role in neuron cell survival and autophagy. Abnormal expression and chromosomal translocations of this gene are associated with cancer progression in numerous tissues. Alternate splicing results in multiple transcript variants.
Gene Details:
Apoptosis regulator Bcl-2
Host:
Mouse
Immunogen:
Murine Bcl-2 peptide (a.a. 61-76)
Isotype:
IgG1
Protein Details:
apoptosis regulator Bcl-2
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody