GDF15 Antibody
Product Sizes
25 µL
£333.00
OARA02165-25UL
About this Product
- SKU:
- OARA02165
- Additional Names:
- GDF-15;growth/differentiation factor 15;macrophage inhibitory cytokine 1;MIC1;MIC-1;NAG-1;non-steroidal anti-inflammatory drug-activated gene-1;NRG-1;NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1;NSAID-activated gene 1 protein;NSAID-regulated gene 1 protein;PDF;PLAB;placental bone morphogenetic protein;placental TGF-beta;prostate differentiation factor;PTGFB;PTGF-beta.
- translate.label.attr.clone:
- 23B3D2.H5
- Clonality:
- Monoclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1.13 mg/ml
- Extra Details:
- Regulates food intake; energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099; PubMed:23468844; PubMed:29046435). Binds to its receptor; GFRAL; and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PubMed:28953886; PubMed:28846097; PubMed:28846098; PubMed:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala; which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions (PubMed:28953886). On hepatocytes; inhibits growth hormone signaling (By similarity).
- Gene Details:
- growth differentiation factor 15
- Host:
- Mouse
- Immunogen:
- This Protein A purified antibody was prepared by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminal end of human NAG-1 protein. A residue of cysteine was added to facilitate coupling to KLH.
- Protein Details:
- Growth/differentiation factor 15
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -20Â[o]C|See manual
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
