Anti-GABA Transporter
Product Sizes
100 ul
£587.00
OAPC00137-100UL
About this Product
- SKU:
- OAPC00137
- Additional Names:
- Gat1; Gabt1
- Clonality:
- Polyclonal
- Extra Details:
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system; causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date; four distinct GABA transporters have been identified: GAT-1; GAT-2; GAT-3; and BGT-1. GAT-1; the most abundant of the transporters; is found predominantly in neurons; but also in some specialized glia (Minelli et al.; 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003).
- Host:
- Rabbit
- Immunogen:
- Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-1.
- Molecular Weight:
- ~67kDa
- Protein Details:
- Sodium- and chloride-dependent GABA transporter 1
- Purification:
- Prepared from rabbit serum by affinity purification.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For long term storage -20C is recommended. Stable at -20C for at least 1 year.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
