Anti-GAP-43
Product Sizes
100 ul
£522.00
OAPC00136-100UL
About this Product
- SKU:
- OAPC00136
- Additional Names:
- Basp2
- Clonality:
- Polyclonal
- Concentration:
- 15 mg/ml
- Extra Details:
- GAP-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration (Benowitz and Routtenberg; 1997). There is also evidence from knockout animals that GAP-43 serves to amplify pathfinding signals from the growth cone (Strittmatter et al.; 1995). GAP-43 is thought to mediate at least some of these effects via interaction with actin. Importantly; phosphorylation at Ser41 by protein kinase C modulates the interaction of GAP-43 with actin (He et al.; 1997) and may also affect neurotransmitter release during forms of plasticity like LTP (Hulo et al.; 2002).
- Immunogen:
- Synthetic peptide corresponding to amino acid residues from the C-terminal region of the rat GAP43 sequence.
- Molecular Weight:
- ~43kDa
- Protein Details:
- Neuromodulin
- Purification:
- Total IgY fraction.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For long term storage -20C is recommended. Stable at -20C for at least 1 year.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
