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Antibodies

Anti-COBRA 1

Product Sizes
100 ul
£587.00
OAPC00093-100UL
About this Product
SKU:
OAPC00093
Additional Names:
COBRA1; NELF-B
translate.label.attr.clone:
F7E4
Clonality:
Monoclonal
Extra Details:
COBRA1 (cofactor of BRCA1) also known as NELF-B; is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ER alpha) and repress ER alpha -mediated transcription (Aiyar SE et al.; 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation; differentiation; apoptosis and oncogeneis (Zhong H et al.; 2004)
Host:
Mouse
Immunogen:
Recombinant full length human COBRA1 purified from E. coli
Isotype:
IgG<sup>1</sup>
Molecular Weight:
~62kDa
Protein Details:
Negative elongation factor B
Purification:
Protein G purified culture supernatant.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C; stable for at least one year.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody