Anti-Beta III Tubulin
Product Sizes
100 ul
£587.00
OAPC00075-100UL
About this Product
- SKU:
- OAPC00075
- translate.label.attr.clone:
- AA10
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Tubulin is the major constituent of microtubules; existing as a heterodimer of the alpha and beta subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific; posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins (Lee et al.; 1990). Additionally; beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer; large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy (Katsetos et al.; 2003)
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to beta III tubulin.
- Isotype:
- IgG
- Molecular Weight:
- ~55kDa
- Protein Details:
- Tubulin beta-3 chain
- Purification:
- Protein G purified culture supernatant.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For long-term storage; -80C is recommended; but shorter-term storage at -20C is also acceptable as aliquots may be taken without freezing/thawing due to the presence of 50% glycerol. Stock solutions are stable for a minimum of 1 year at -20C.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
