Anti-Tryptophan Hydroxylase
Product Sizes
100 ul
£587.00
OAPC00074-100UL
About this Product
- SKU:
- OAPC00074
- Additional Names:
- TPH
- Clonality:
- Polyclonal
- Extra Details:
- Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin (Martinez et al.; 2001). Thus; expression of TPH can be used as an indicator of the localization of serotonin and melatonin in brain. In mammals; serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain; and melatonin synthesis takes place within the pineal gland (Haycock et al.; 2002). Although TPH catalyzes the same reaction within the Raphe nuclei and the pineal gland; TPH activity is rate-limiting for serotonin but not melatonin biosynthesis (Martinez et al.; 2001).
- Host:
- Sheep
- Immunogen:
- Recombinant rabbit tryptophan hydroxylase; isolated as inclusion bodies from E. coli and purified by preparative SDS-PAGE.
- Molecular Weight:
- ~55kDa
- Protein Details:
- Tryptophan 5-hydroxylase 1
- Purification:
- Prepared from sheep serum by affinity purification using a column to which the recombinant protein was coupled.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For long term storage -20C is recommended. Stable at -20C for at least 1 year.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
