Anti-Synaptobrevin
Product Sizes
100 ul
£587.00
OAPC00064-100UL
About this Product
- SKU:
- OAPC00064
- Additional Names:
- SYB1; CMS25; SPAX1; VAMP-1
- translate.label.attr.clone:
- SP10
- Clonality:
- Monoclonal
- Extra Details:
- Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes; along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al.; 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease (Sze et al.; 2000).
- Host:
- Mouse
- Immunogen:
- Synaptic immunoprecipitate (crude) from human brain.
- Isotype:
- IgM
- Molecular Weight:
- ~16kDa
- Protein Details:
- Vesicle-associated membrane protein 1
- Purification:
- Purified culture supernatant.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C; stable for at least one year.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
