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Antibodies

Anti-Periostin; C-terminal

Product Sizes
100 ul
£587.00
OAPC00052-100UL
About this Product
SKU:
OAPC00052
Additional Names:
p; Os; PN; Pe; OSF; PLF; Osf2; OSF-2; AI747096; A630052E07Rik
Clonality:
Polyclonal
Concentration:
0.25 mg/ml
Extra Details:
Periostin is a matricellular protein; i.e. an extracellular matrix protein that interacts both with other ECM proteins and with cell-surface receptors. Like many other matricellular proteins; the function of periostin is important both in embryonic development and in the remodeling of adult tissues in response to pathological insults. Periostin was originally isolated as an osteoblast-specific marker that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment; attachment and spreading (Kruzynska-Frejtag A. et al.; 2004). Periostin has since been demonstrated to be important in heart valve development and myocardial infarction because it promotes collagen fibrogenesis; inhibits differentiation of progenitor cells into cardiomyocytes and is essential in maintaining the biomechanical properties of the adult myocardium (Norris et al.; 2008).
Host:
Rabbit
Immunogen:
Bacterial fusion protein equivalent to a 188-amino acid polypeptide from the C-terminal region of mouse periostin which is comprised of six small alternatively-spliced exons.
Molecular Weight:
~93kDa
Protein Details:
Periostin
Purification:
Prepared from rabbit serum by affinity purification using a column to which the fusion protein immunogen was coupled.
Shipping Conditions:
Blue Ice
Storage Conditions:
For long term storage -80°C is recommended; but shorter term storage at -20°C is also acceptable. Stable for a minimum of 1 year at -20°C. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody