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Antibodies

Anti-NMDA Receptor, NR1 Subunit, C2 Splice Variant Insert

Product Sizes
Anti-NMDA Receptor, NR1 Subunit, C2 Splice Variant Insert
£ POA
OAPC00041
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
OAPC00041
Application:
Western Blot, Immunohistochemistry
Clonality:
Polyclonal
Format:
Lyophilized from 5 mM ammonium bicarbonate. Adequate amount of material to conduct 10-mini Western Blots.
Gene Details:
GRIN1
Host:
Rabbit
Molecular Weight:
~120kDa
Protein Details:
Glutamate receptor ionotropic, NMDA 1
Purification:
Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
References:
Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci 25:571-577.<br/>Foldes RL, Rampersad V, Kamboj RK (1994) Cloning and sequence analysis of additional splice variants encoding human N-methyl-D-aspartate receptor (hNR1) subunits. Gene 147:303-304.<br/>Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33.<br/>Wenthold RJ, Prybylowski K, Standley S, Sans N, Petralia RS (2003) Trafficking of NMDA receptors. Annu Rev Pharmacol Toxicol 43:335-358.<br/>Zukin RS, Bennett MVL (1995) Alternatively spliced isoforms of the NMDARI receptor subunit. Trends Neurosci 18:306-313.<br/>Mannie M. Y. Fan, Herman B. Fernandes, Lily Y. J. Zhang, Michael R. Hayden, and Lynn A. Raymond (2007) Altered NMDA Receptor Trafficking in a Yeast Artificial Chromosome Transgenic Mouse Model of Huntington's DiseaseJ. Neurosci., 27: 3768 - 3779.<br/>Note: Dr. Michael Browning, a co-author of one of the cited papers, is President and founder of PhosphoSolutions.
Shipping Conditions:
Blue Ice
Storage Conditions:
For long term storage -20C is recommended. Stable at -20C for at least 1 year. The antibody should be reconstituted
in 50 ul phosphate buffered saline (PBS: 137 mM NaCl, 7.5 mM Na2HPO4, 2.7 mM KCl, 1.5 mM KH2PO4, pH 7.4) before use. After
reconstitution the antibody should be aliquoted and stored at -20C.
Supplier:
Aviva Systems Biology
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