Anti-NMDA Receptor, NR2A Subunit N-terminus
Product Sizes
Anti-NMDA Receptor, NR2A Subunit N-terminus
£ POA
OAPC00035
About this Product
- SKU:
- OAPC00035
- Application:
- Western Blot, Immunohistochemistry
- Clonality:
- Polyclonal
- Format:
- Liquid. 100 ul antibody vial in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug BSA per ml and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
- Gene Details:
- GRIN2A
- Host:
- Rabbit
- Molecular Weight:
- ~180kDa
- Protein Details:
- Glutamate receptor ionotropic, NMDA 2A
- Purification:
- Prepared from rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.
- References:
- Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD (2003) Tyrosine dephosphorylation and ethanol inhibition of N-methyl-D-aspartate receptor function. J Biol Chem 278:11020-11025.<br/>Carroll RC, Zukin RS (2002) NMDA-receptor trafficking and targeting: implications for synaptic transmission and plasticity. Trends Neurosci 25:571-577.<br/>Grosshans DR, Clayton DA, Coultrap SJ, Browning MD (2002) LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci 5:27-33.<br/>Lovinger DM, White G, Weight FF (1989) Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243:1721-1724.<br/>Lu W-Y, Xiong Z-G, Lei S, Orser BA, Browning MD, MacDonald JF (1999) G-protein coupled receptors act via protein kinase C and Src to regulate NMDA receptors. Nature Neurosci 2:331-338.<br/>Snell LD, Nunley KR, Lickteig RL, Browning MD, Tabakoff B, Hoffman PL (1996) Regional and subunit specific changes in NMDA receptor mRNA and immunoreactivity in mouse brain following chronic ethanol ingestion. Mol Brain Res 40:71-78.<br/>Wenthold RJ, Prybylowski K, Standley S, Sans N, Petralia RS (2003) Trafficking of NMDA receptors. Annu Rev Pharmacol Toxicol 43:335-358.<br/>Note: Dr. Michael Browning, a co-author of four of the cited papers, is President and founder of PhosphoSolutions.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C; stable for at least 1 year
- Supplier:
- Aviva Systems Biology
- Manufacturer's Data Sheet:html_datasheet.php
