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Antibodies

Anti-Neurofilament M

Product Sizes
100 ul
£522.00
OAPC00029-100UL
About this Product
SKU:
OAPC00029
Additional Names:
Nfm; Nef3
Clonality:
Polyclonal
Extra Details:
Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons; and are composed predominantly of three major proteins called NF-L; NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa; with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases; such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2).
Immunogen:
Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.
Molecular Weight:
~145kDa
Protein Details:
Neurofilament medium polypeptide
Purification:
Total IgY fraction.
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at -20C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody