Anti-Neurofilament M
Product Sizes
100 ul
£543.00
OAPC00028-100UL
About this Product
- SKU:
- OAPC00028
- Additional Names:
- Nfm; Nef3
- Clonality:
- Monoclonal
- Extra Details:
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons; and are composed predominantly of three major proteins called NF-L; NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa; with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases; such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2).
- Host:
- Mouse
- Immunogen:
- Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E. coli.
- Isotype:
- IgG1
- Molecular Weight:
- ~145kDa
- Protein Details:
- Neurofilament medium polypeptide
- Purification:
- Unpurified; concentrated culture supernatant.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20C in undiluted aliquots; stable for at least 1 year. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
