Anti-Nestin
Product Sizes
100 ul
£587.00
OAPC00021-100UL
About this Product
- SKU:
- OAPC00021
- Additional Names:
- Nbla00170
- translate.label.attr.clone:
- 4D11
- Clonality:
- Monoclonal
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- Nestin is a member of the class IV intermediate filament protein family which is expressed in neuronal stem cells (Lendahl et al.; 1990). Nestin was originally identified as a result of the production of a series of monoclonal antibodies directed against epitopes expressed on formalin fixed embryo day 15 rat spinal cord (Hockfield et al.; 1985)). One of these antibodies; called Rat 401; stained fibrous profiles in the developing nervous system; but not in the mature nervous system. By screening bacteriophage expression libraries with Rat 401; Lendahl et al. were able to isolate a cDNA encoding the protein to which Rat 401 antibody bound. The protein proved to be an unusual member of the intermediate filament family; containing an alpha-helical region homologous to that found in keratin and neurofilament subunits.
- Host:
- Mouse
- Immunogen:
- Recombinant partial segment of human nestin expressed in and purified from E.coli.
- Isotype:
- IgG1
- Molecular Weight:
- ~220-240kDa
- Protein Details:
- Nestin
- Purification:
- Protein G purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at -20°C; stable for at least one year. Avoid freeze/thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
