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Antibodies

C2CD3 Antibody - N-terminal

Product Sizes
0.1 mg
£652.00
OAPB02020-0.1MG
About this Product
SKU:
OAPB02020
Additional Names:
C2 calcium dependent domain containing 3;C2 domain-containing protein 3;OFD14.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage; a structure at the distal end of the mother centriole that acts as an anchor of the cilium; and is required for recruitment of centriolar distal appendages proteins CEP83; SCLT1; CEP89; FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.
Gene Details:
C2 domain containing 3 centriole elongation regulator
Host:
Rabbit
Immunogen:
C2CD3 antibody was raised against an 18 amino acid peptide near the center of human C2CD3. The immunogen is located within amino acids 1490 - 1540 of C2CD3.
Isotype:
IgG
Molecular Weight:
Predicted: 216; 259 kDa Observed: 255 kDa
Protein Details:
C2 domain-containing protein 3|C2 domain-containing protein 3 isoform 1 [Homo sapiens]
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody