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Antibodies

ATG4D Antibody - N-terminal

Product Sizes
0.1 mg
£652.00
OAPB01985-0.1MG
About this Product
SKU:
OAPB01985
Additional Names:
APG4 autophagy 4 homolog D;APG4D;APG4-D;ATG4 autophagy related 4 homolog D;AUTL4;AUT-like 4 cysteine endopeptidase;autophagin-4;autophagy-related cysteine endopeptidase 4;autophagy-related protein 4 homolog D;cysteine protease ATG4D;cysteine protease involved in autophagy.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2; to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Gene Details:
autophagy related 4D cysteine peptidase
Host:
Rabbit
Immunogen:
ATG4D antibody was raised against a 17 amino acid peptide near the amino terminus of human ATG4D. The immunogen is located within the first 50 amino acids of ATG4D.
Isotype:
IgG
Molecular Weight:
Predicted: 52 kDa Observed: 49 kDa
Protein Details:
Cysteine protease ATG4D|cysteine protease ATG4D isoform 1 precursor [Homo sapiens]
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody