ATG4B Antibody - C-terminal
Product Sizes
0.1 mg
£652.00
OAPB01984-0.1MG
About this Product
- SKU:
- OAPB01984
- Additional Names:
- APG4 autophagy 4 homolog B;APG4B;ATG4 autophagy related 4 homolog B;AUTL1;AUT-like 1 cysteine endopeptidase;autophagin-1;autophagy-related cysteine endopeptidase 1;autophagy-related protein 4 homolog B;cysteine protease ATG4B;hAPG4B.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3; GABARAPL1; GABARAPL2 and GABARAP; to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes; which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
- Gene Details:
- autophagy related 4B cysteine peptidase
- Host:
- Rabbit
- Immunogen:
- ATG4B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ATG4B. The immunogen is located within the last 50 amino acids of ATG4B.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 43 kDa Observed: 46 kDa
- Protein Details:
- Cysteine protease ATG4B|cysteine protease ATG4B isoform a [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
