APOBEC3B Antibody - N-terminal
Product Sizes
0.1 mg
£652.00
OAPB01875-0.1MG
About this Product
- SKU:
- OAPB01875
- Additional Names:
- A3B;APOBEC1L;apolipoprotein B mRNA editing enzyme; catalytic polypeptide-like 3B;ARCD3;ARP4;bK150C2.2;cytidine deaminase;DJ742C19.2;DNA dC->dU-editing enzyme APOBEC-3B;phorbolin 2;phorbolin 3;phorbolin-1-related protein;phorbolin-2/3;PHRBNL;probable DNA dC->dU-editing enzyme APOBEC-3B.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription; it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA; leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome; along with a deamination-independent mechanism that works prior to the proviral integration; together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV); hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.
- Gene Details:
- apolipoprotein B mRNA editing enzyme catalytic subunit 3B
- Host:
- Rabbit
- Immunogen:
- APOBEC3B antibody was raised against a 14 amino acid peptide near the amino terminus of human APOBEC3B. The immunogen is located within amino acids 20 - 70 of APOBEC3B.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 42 kDa Observed: 48 kDa
- Protein Details:
- DNA dC->dU-editing enzyme APOBEC-3B|DNA dC->dU-editing enzyme APOBEC-3B isoform a [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
