DCP2 Antibody - C-terminal
Product Sizes
0.1 mg
£652.00
OAPB01653-0.1MG
About this Product
- SKU:
- OAPB01653
- Additional Names:
- DCP2 decapping enzyme homolog;hDpc;m7GpppN-mRNA hydrolase;mRNA-decapping enzyme 2;Nucleoside diphosphate-linked moiety X motif 20;nudix (nucleoside diphosphate linked moiety X)-type motif 20;NUDT20.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs (PubMed:12417715; PubMed:12218187; PubMed:12923261; PubMed:21070968). Removes the 7-methyl guanine cap structure from mRNA molecules; yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (PubMed:12486012; PubMed:12923261; PubMed:21070968). Necessary for the degradation of mRNAs; both in normal mRNA turnover and in nonsense-mediated mRNA decay (PubMed:14527413). Plays a role in replication-dependent histone mRNA degradation (PubMed:18172165). Has higher activity towards mRNAs that lack a poly(A) tail (PubMed:21070968). Has no activity towards a cap structure lacking an RNA moiety (PubMed:21070968). Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degration of their transcripts (PubMed:26098573).
- Gene Details:
- decapping mRNA 2
- Host:
- Rabbit
- Immunogen:
- DCP2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DCP2. The immunogen is located within amino acids 340 - 390 of DCP2.
- Isotype:
- IgG
- Molecular Weight:
- 46 kDa
- Protein Details:
- m7GpppN-mRNA hydrolase|m7GpppN-mRNA hydrolase isoform 1 [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
