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Antibodies

CCP110 Antibody - C-terminal

Product Sizes
0.1 mg
£652.00
OAPB01578-0.1MG
About this Product
SKU:
OAPB01578
Additional Names:
centriolar coiled-coil protein 110kDa;centriolar coiled-coil protein of 110 kDa;centrosomal protein CP110;centrosomal protein of 110 kDa;Cep110;CP110.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131; PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Gene Details:
centriolar coiled-coil protein 110
Host:
Rabbit
Immunogen:
CCP110 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CCP110. The immunogen is located within the last 50 amino acids of CCP110.
Isotype:
IgG
Molecular Weight:
Predicted: 110 kDa Observed: 110 kDa
Protein Details:
Centriolar coiled-coil protein of 110 kDa|centriolar coiled-coil protein of 110 kDa isoform 1 [Homo sapiens]
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody