JMJD3 Antibody - N-terminal
Product Sizes
0.1 mg
£652.00
OAPB01529-0.1MG
About this Product
- SKU:
- OAPB01529
- Additional Names:
- [histone H3]-trimethyl-L-lysine(27) demethylase 6B;jmjC domain-containing protein 3;JMJD3;jumonji domain containing 3; histone lysine demethylase;jumonji domain-containing protein 3;lysine (K)-specific demethylase 6B;Lysine demethylase 6B;lysine-specific demethylase 6B;NEDCFSA.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Histone demethylase that specifically demethylates 'Lys-27' of histone H3; thereby playing a central role in histone code (PubMed:17825402; PubMed:17851529; PubMed:17713478; PubMed:18003914). Demethylates trimethylated and dimethylated H3 'Lys-27' (PubMed:17825402; PubMed:17851529; PubMed:17713478; PubMed:18003914). Plays a central role in regulation of posterior development; by regulating HOX gene expression (PubMed:17851529). Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402). Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (By similarity).
- Gene Details:
- lysine demethylase 6B
- Host:
- Rabbit
- Immunogen:
- Anti-JMJD3 antibody (6657) was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human JMJD3. The immunogen is located within amino acids 1370-1420 of JMJD3.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 180 Observed: 180 kD
- Protein Details:
- hCG2036579; isoform CRA_a [Homo sapiens]|Lysine-specific demethylase 6B
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
