ANKLE2 Antibody - N-terminal
Product Sizes
0.1 mg
£652.00
OAPB01509-0.1MG
About this Product
- SKU:
- OAPB01509
- Additional Names:
- ankyrin repeat and LEM domain-containing protein 2;KIAA0692;LEM domain containing 7;LEM domain-containing protein 4;Lem4;LEMD7;MCPH16.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit. Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A); thereby facilitating nuclear envelope assembly. It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex. Involved in brain development (PubMed:25259927).
- Gene Details:
- ankyrin repeat and LEM domain containing 2
- Immunogen:
- ANKLE2 antibody was raised against a 19 amino acid synthetic peptide near the center of human ANKLE2. The immunogen is located within amino acids 280 - 330 of ANKLE2.
- Isotype:
- IgY
- Molecular Weight:
- Predicted: 121; 139; 145 kDa Observed: 121 kDa
- Protein Details:
- ANKLE2 protein [Homo sapiens]|Ankyrin repeat and LEM domain-containing protein 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
