BRUCE Antibody - C-terminal
Product Sizes
0.1 mg
£652.00
OAPB01419-0.1MG
About this Product
- SKU:
- OAPB01419
- Additional Names:
- APOLLON;baculoviral IAP repeat-containing protein 6;BIR repeat-containing ubiquitin-conjugating enzyme;BRUCE;RING-type E3 ubiquitin transferase BIRC6;Ubiquitin-conjugating BIR domain enzyme apollon;ubiquitin-conjugating BIR-domain enzyme apollon.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide; ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity; forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3; CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission; but also for the integrity of the midbody and the midbody ring; and its striking ubiquitin modification.
- Gene Details:
- baculoviral IAP repeat containing 6
- Host:
- Rabbit
- Immunogen:
- BRUCE antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human BRUCE. The immunogen is located within amino acids 4760 - 4810 of BRUCE.
- Isotype:
- IgG
- Molecular Weight:
- 534 kDa
- Protein Details:
- Baculoviral IAP repeat-containing protein 6|baculoviral IAP repeat-containing protein 6 [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
