SCF Antibody
Product Sizes
0.1 mg
£652.00
OAPB00887-0.1MG
About this Product
- SKU:
- OAPB00887
- Additional Names:
- c-Kit ligand;DCUA;DFNA69;familial progressive hyperpigmentation 2;FPH2;FPHH;kit ligand;Kitl;KL-1;mast cell growth factor;MGF;SCF;SF;SHEP7;SLF;steel factor;stem cell factor.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation; hematopoiesis; stem cell maintenance; gametogenesis; mast cell development; migration and function; and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1; the regulatory subunit of phosphatidylinositol 3-kinase; and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS; RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1; STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1; leading to the production of the cellular signaling molecules diacylglycerol and inositol 1;4;5-trisphosphate. KITLG/SCF acts synergistically with other cytokines; probably interleukins.
- Gene Details:
- KIT ligand
- Host:
- Rabbit
- Immunogen:
- Anti-SCF antibody (5165) was raised against a peptide corresponding to 18 amino acids near the center of human SCF. The immunogen is located within amino acids 100-150 of SCF.
- Molecular Weight:
- Predicted: 31kD Observed: 36 kD (31kD + 4 N-linked Glycosylations)
- Protein Details:
- Kit ligand
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- SCF antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
