POLR3F Antibody
Product Sizes
0.1 mg
£652.00
OAPB00722-0.1MG
About this Product
- SKU:
- OAPB00722
- Additional Names:
- C34;DNA-directed RNA polymerase III subunit F;DNA-directed RNA polymerase III subunit RPC6;polymerase (RNA) III (DNA directed) polypeptide F; 39 kDa;polymerase (RNA) III subunit F;RNA polymerase III 39 kDa subunit;RNA polymerase III C39 subunit;RNA polymerase III subunit C6;RPC39;RPC6.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs; such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts; such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway. Preferentially binds double-stranded DNA (dsDNA) (PubMed:21358628).
- Gene Details:
- RNA polymerase III subunit F
- Host:
- Rabbit
- Immunogen:
- POLR3F antibody was raised against a 21 amino acid synthetic peptide from near the amino terminus of human POLR3F. The immunogen is located within the first 50 amino acids of POLR3F.
- Protein Details:
- DNA-directed RNA polymerase III subunit RPC6|polymerase (RNA) III (DNA directed) polypeptide F; 39 kDa [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- POLR3F antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
