SATB2 Antibody
Product Sizes
0.1 mg
£652.00
OAPB00691-0.1MG
About this Product
- SKU:
- OAPB00691
- Additional Names:
- DNA-binding protein SATB2;GLSS;SATB family member 2;special AT-rich sequence-binding protein 2.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Binds to DNA; at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression; by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes; probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.
- Gene Details:
- SATB homeobox 2
- Host:
- Rabbit
- Immunogen:
- SATB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human SATB2. The immunogen is located within amino acids 570 - 620 of SATB2.
- Protein Details:
- DNA-binding protein SATB2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- SATB2 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
