TARDBP Antibody
Product Sizes
0.1 mg
£652.00
OAPB00553-0.1MG
About this Product
- SKU:
- OAPB00553
- Additional Names:
- ALS10;TAR DNA-binding protein 43;TAR DNA-binding protein-43;TDP-43.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis; apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
- Gene Details:
- TAR DNA binding protein
- Host:
- Rabbit
- Immunogen:
- TDP43 antibody was raised against a 18 amino acid synthetic peptide from near the center of human TDP43. The immunogen is located within amino acids 160 - 210 of TDP43.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 46 kDa Observed: 46 kDa
- Protein Details:
- TAR DNA-binding protein 43|TDP43 [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- TDP43 antibody can be stored at 4C for three months and -20C; stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
