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Antibodies

TLR9 Antibody

Product Sizes
0.1 mg
£652.00
OAPB00382-0.1MG
About this Product
SKU:
OAPB00382
Additional Names:
CD289;toll-like receptor 9.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6; leading to NF-kappa-B activation; cytokine secretion and the inflammatory response (PubMed:11564765; PubMed:17932028). Controls lymphocyte response to Helicobacter infection (By similarity). Upon CpG stimulation; induces B-cell proliferation; activation; survival and antibody production (PubMed:23857366).
Gene Details:
toll like receptor 9
Host:
Rabbit
Immunogen:
TLR9 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human TLR9. The immunogen is located within amino acids 960 - 1010 of TLR9.
Protein Details:
Toll-like receptor 9|Toll-like receptor 9 [Homo sapiens]
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
TLR9 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody