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Antibodies

TLR3 Antibody

Product Sizes
0.1 mg
£652.00
OAPB00359-0.1MG
About this Product
SKU:
OAPB00359
Additional Names:
CD283;IIAE2;IMD83;toll-like receptor 3.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA; a sign of viral infection. Acts via the adapter TRIF/TICAM1; leading to NF-kappa-B activation; IRF3 nuclear translocation; cytokine secretion and the inflammatory response.
Gene Details:
toll like receptor 3
Host:
Rabbit
Immunogen:
TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR3. The immunogen is located within amino acids 780 - 830 of TLR3.
Molecular Weight:
Predicted: 99 kDa Observed: 105 kDa
Protein Details:
Toll-like receptor 3
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2Â[o]C to 8Â[o]C
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody