BECN1 Antibody
Product Sizes
0.1 mg
£652.00
OAPB00348-0.1MG
About this Product
- SKU:
- OAPB00348
- Additional Names:
- ATG6;ATG6 autophagy related 6 homolog;beclin 1 (coiled-coil; moesin-like BCL2-interacting protein);beclin 1; autophagy related;beclin1;beclin-1;coiled-coil myosin-like BCL2-interacting protein;Protein GT197;testis secretory sperm-binding protein Li 215e;VPS30.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Plays a central role in autophagy (PubMed:23184933; PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis; probably in the context of PI3KC3-C2 (PubMed:20643123; PubMed:20208530; PubMed:26783301). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
- Gene Details:
- beclin 1
- Host:
- Rabbit
- Immunogen:
- Anti-Beclin-1 antibody (3613) was raised against a peptide corresponding to 17 amino acids near the center of human Beclin-1. The immunogen is located between 40-90 amino acids of Beclin-1.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 52 kD Observed: 60 kD
- Protein Details:
- Beclin 1; autophagy related [Homo sapiens]|Beclin-1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
