Bax Antibody
Product Sizes
0.1 mg
£652.00
OAPB00247-0.1MG
About this Product
- SKU:
- OAPB00247
- Additional Names:
- apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4;bcl-2-like protein 4.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Plays a role in the mitochondrial apoptotic process. Under normal conditions; BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL; which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions; undergoes a conformation change that causes translocation to the mitochondrion membrane; leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3; and thereby apoptosis.
- Gene Details:
- BCL2 associated X; apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax. The immunogen is located within the first 50 amino acids of Bax.
- Protein Details:
- Apoptosis regulator BAX|Bax alpha [Homo sapiens]
- Purification:
- Ion Exchange
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Bax antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
