Bcl-2 Antibody
Product Sizes
0.1 mg
£652.00
OAPB00242-0.1MG
About this Product
- SKU:
- OAPB00242
- Additional Names:
- apoptosis regulator Bcl-2;B-cell CLL/lymphoma 2;Bcl-2;PPP1R50;protein phosphatase 1; regulatory subunit 50.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation; hence CASP1 activation and IL1B release (PubMed:17418785).
- Gene Details:
- BCL2 apoptosis regulator
- Host:
- Rabbit
- Immunogen:
- Anti-Bcl-2 antibody (3335) was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bcl-2. The immunogen is located within the first 50 amino acids of Bcl-2.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 26kD Observed: 26 kD
- Protein Details:
- Apoptosis regulator Bcl-2|B-cell CLL/lymphoma 2 [Homo sapiens]
- Purification:
- Ion Exchange
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Bcl-2antibody can be stored at 4C; for three months and -20C stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
