SARM Antibody
Product Sizes
0.1 mg
£652.00
OAPB00233-0.1MG
About this Product
- SKU:
- OAPB00233
- Additional Names:
- hSARM1;HsTIR;MyD88-5;NAD(+) hydrolase SARM1;NADase SARM1;NADP(+) hydrolase SARM1;SAM domain-containing protein 2;SAMD2;SARM;sterile alpha and Armadillo repeat protein;sterile alpha and HEAT/Armadillo motif protein; ortholog of Drosophila;sterile alpha and TIR motif-containing protein 1;sterile alpha motif domain-containing protein 2;tir-1 homolog.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1; TRIF-dependent activation of NF-kappa-B and IRF3; and the phosphorylation of MAPK14/p38.
- Gene Details:
- sterile alpha and TIR motif containing 1
- Host:
- Rabbit
- Immunogen:
- SARM antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human SARM. The immunogen is located within amino acids 640 - 690 of SARM.
- Molecular Weight:
- Predicted: 80 kDa Observed: 85 kDa
- Protein Details:
- Sterile alpha and TIR motif-containing protein 1|sterile alpha and TIR motif-containing protein 1 precursor [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2Â[o]C to 8Â[o]C
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
