TRIF Antibody
Product Sizes
0.1 mg
£652.00
OAPB00204-0.1MG
About this Product
- SKU:
- OAPB00204
- Additional Names:
- IIAE6;MyD88-3;proline-rich; vinculin and TIR domain-containing protein B;PRVTIRB;putative NF-kappa-B-activating protein 502H;TICAM-1;TIR domain containing adaptor inducing interferon-beta;TIR domain-containing adapter molecule 1;TIR domain-containing adapter protein inducing IFN-beta;toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta;TRIF.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation; and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1; TRAF6 and RIPK1; which in turn; lead to the activation of transcription factors IRF3 and IRF7; NF-kappa-B and FADD respectively.
- Gene Details:
- toll like receptor adaptor molecule 1
- Host:
- Rabbit
- Immunogen:
- TRIF antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRIF. The immunogen is located within the last 50 amino acids of TRIF.
- Molecular Weight:
- Predicted: 60 kDa Observed: 55 kDa
- Protein Details:
- TIR domain-containing adapter molecule 1|TIR domain-containing adapter molecule 1 [Homo sapiens]
- Purification:
- Ion Exchange
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- TRIF antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
