AICDA Antibody
Product Sizes
0.1 mg
£652.00
OAPB00184-0.1MG
About this Product
- SKU:
- OAPB00184
- Additional Names:
- Activation-induced cytidine deaminase;AID;ARP2;CDA2;cytidine aminohydrolase;epididymis secretory protein Li 284;HEL-S-284;HIGM2;integrated into Burkitt's lymphoma cell line Ramos;single-stranded DNA cytosine deaminase.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM); gene conversion; and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (V) and Ig-switch (S) region DNA. Required for several crucial steps of B-cell terminal differentiation necessary for efficient antibody responses (PubMed:18722174; PubMed:21385873; PubMed:21518874; PubMed:27716525). May also play a role in the epigenetic regulation of gene expression by participating in DNA demethylation (PubMed:21496894).
- Gene Details:
- activation induced cytidine deaminase
- Host:
- Rabbit
- Immunogen:
- AID antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human AID. The immunogen is located within the last 50 amino acids of AID.
- Molecular Weight:
- Predicted: 22 kDa Observed: 25 kDa
- Protein Details:
- AID; partial [Homo sapiens]|Single-stranded DNA cytosine deaminase
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- AID antibody can be stored at 4C for three months and -20C for up to one year. As with all antibodies care should be taken to avoid repeated freeze/thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
