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Antibodies

BACE Antibody

Product Sizes
0.1 mg
£652.00
OAPB00100-0.1MG
About this Product
SKU:
OAPB00100
Additional Names:
APP beta-secretase;asp 2;ASP2;aspartyl protease 2;BACE;beta-secretase 1;beta-secretase 1 precursor variant 1;beta-site amyloid beta A4 precursor protein-cleaving enzyme;Beta-site amyloid precursor protein cleaving enzyme 1;beta-site APP cleaving enzyme 1;beta-site APP-cleaving enzyme;HSPC104;memapsin-2;membrane-associated aspartic protease 2;transmembrane aspartic proteinase Asp2.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence; between residues 671 and 672 of APP; leads to the generation and extracellular release of beta-cleaved soluble APP; and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Gene Details:
beta-secretase 1
Host:
Rabbit
Immunogen:
Anti-BACE antibody (2253) was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BACE. The immunogen is located within the last 50 amino acids of BACE.
Molecular Weight:
Predicted: 55kD Observed: 65kD (Post-modification: 4 N-linked glycosylation)
Protein Details:
Beta-secretase 1|Homo sapiens beta-site APP cleaving enzyme (BACE) mRNA; complete cds
Purification:
Ion Exchange
Shipping Conditions:
Blue Ice
Storage Conditions:
BACE antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody