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Antibodies

Apaf1 Antibody

Product Sizes
0.1 mg
£652.00
OAPB00040-0.1MG
About this Product
SKU:
OAPB00040
Additional Names:
APAF-1;apoptotic protease-activating factor 1;CED4.
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
1 mg/ml
Extra Details:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3); leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Gene Details:
apoptotic peptidase activating factor 1
Host:
Rabbit
Immunogen:
Apaf1 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human Apaf1. The sequence of the immunogenic peptide differs from that of murine Apaf1 by one amino acid. The immunogen is located within the last 50 amino acids of Apaf1.
Molecular Weight:
130 kDa
Protein Details:
apoptotic protease activating factor 1 [Homo sapiens]|Apoptotic protease-activating factor 1
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Apaf1 antibody can be stored at 4C; stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody