CXCR4 Antibody
Product Sizes
0.1 mg
£652.00
OAPB00002-0.1MG
About this Product
- SKU:
- OAPB00002
- Additional Names:
- CD184;CD184 antigen;chemokine (C-X-C motif) receptor 4;C-X-C chemokine receptor type 4;D2S201E;FB22;fusin;HM89;HSY3RR;LAP3;LAP-3;LCR1;LESTR;leukocyte-derived seven transmembrane domain receptor;lipopolysaccharide-associated protein 3;LPS-associated protein 3;neuropeptide Y receptor Y3;neuropeptide Y3 receptor;NPY3R;NPYR;NPYRL;NPYY3R;SDF-1 receptor;seven transmembrane helix receptor;seven-transmembrane-segment receptor; spleen;stromal cell-derived factor 1 receptor;WHIM;WHIMS;WHIMS1.
- Clonality:
- Polyclonal
- Conjugate:
- Unconjugated
- Concentration:
- 1 mg/ml
- Extra Details:
- Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract; probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS; could mediate hippocampal-neuron survival.
- Gene Details:
- C-X-C motif chemokine receptor 4
- Host:
- Rabbit
- Immunogen:
- Anti-CXCR4 antibody (1009) was raised against a peptide corresponding to 14 amino acids near the amino terminus of human CXCR4 isoform b. The immunogen is located within the first 50 amino acids of CXCR4.
- Isotype:
- IgG
- Molecular Weight:
- Predicted: 40 kDa Observed: 44 kDa (Post-modification: 2 N-linked glycosylation)
- Protein Details:
- C-X-C chemokine receptor type 4|C-X-C chemokine receptor type 4 isoform b [Homo sapiens]
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- CXCR4 antibody can be stored at 4C for three months and -20C; stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
