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Antibodies

APEX1 Antibody

Product Sizes
100ul
£630.00
OAGA08732-100UL
About this Product
SKU:
OAGA08732
Additional Names:
APE; APX; APE1; APEN; APEX; HAP1; REF1
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis; by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Gene Details:
apurinic/apyrimidinic endodeoxyribonuclease 1
Host:
Mouse
Immunogen:
Full length human APE1 purified from E. coli
Isotype:
IgG
Protein Details:
DNA-(apurinic or apyrimidinic site) lyase
Purification:
Protein G purified
Shipping Conditions:
Blue Ice
Storage Conditions:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody