BRCA2 Antibody
Product Sizes
100ul
£630.00
OAGA08728-100UL
About this Product
- SKU:
- OAGA08728
- Additional Names:
- FAD; FACD; FAD1; GLM3; BRCC2; FANCD; PNCA2; FANCD1; XRCC11; BROVCA2
- translate.label.attr.clone:
- 5F6
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Inherited mutations in BRCA1 and this gene; BRCA2; confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability; specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif; and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene; as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
- Gene Details:
- BRCA2; DNA repair associated
- Host:
- Mouse
- Immunogen:
- Amino acids 2336-2478 of human BRCA2 expressed in E. coli. BRCA2-P400.
- Isotype:
- IgG1
- Protein Details:
- breast cancer type 2 susceptibility protein
- Purification:
- Protein G purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
