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Antibodies

IL10 Antibody

Product Sizes
100ul
£630.00
OAGA08591-100UL
About this Product
SKU:
OAGA08591
Additional Names:
CSIF; TGIF; GVHDS; IL-10; IL10A
translate.label.attr.clone:
GT5111
Clonality:
Monoclonal
Concentration:
1.19 mg/ml
Extra Details:
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines; MHC class II Ags; and costimulatory molecules on macrophages. It also enhances B cell survival; proliferation; and antibody production. This cytokine can block NF-kappa B activity; and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Gene Details:
interleukin 10
Host:
Mouse
Immunogen:
Recombinant protein encompassing a sequence within the center region of human IL10. The exact sequence is proprietary.
Isotype:
IgG1
Molecular Weight:
21 kDa
Protein Details:
interleukin-10
Purification:
Affinity purified by Protein G.
Shipping Conditions:
Blue Ice
Storage Conditions:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Monoclonal Antibody