INS Antibody
Product Sizes
100ul
£630.00
OAGA08547-100UL
About this Product
- SKU:
- OAGA08547
- Additional Names:
- IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10
- translate.label.attr.clone:
- GT1519
- Clonality:
- Monoclonal
- Concentration:
- 1.62 mg/ml
- Extra Details:
- After removal of the precursor signal peptide; proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides; which are covalently linked via two disulfide bonds to form insulin; and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene; INS-IGF2; which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.
- Gene Details:
- insulin
- Host:
- Mouse
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human insulin. The exact sequence is proprietary.
- Isotype:
- IgG2b
- Protein Details:
- insulin
- Purification:
- Affinity purified by Protein A.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
