TAGLN Antibody
Product Sizes
100ul
£630.00
OAGA08365-100UL
About this Product
- SKU:
- OAGA08365
- Additional Names:
- SM22; SMCC; TAGLN1; WS3-10; SM22-alpha
- translate.label.attr.clone:
- GT4511
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle; and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor; and the loss of its expression is an early event in cell transformation and the development of some tumors; coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization.
- Gene Details:
- transgelin
- Host:
- Mouse
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Transgelin. The exact sequence is proprietary.
- Isotype:
- IgG1
- Protein Details:
- transgelin
- Purification:
- Affinity purified by Protein G.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
