PTPRJ Antibody
Product Sizes
100ul
£630.00
OAGA07859-100UL
About this Product
- SKU:
- OAGA07859
- Additional Names:
- DEP1; SCC1; CD148; HPTPeta; R-PTP-ETA
- Clonality:
- Polyclonal
- Concentration:
- 1.48 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes; including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats; a single transmembrane region; and a single intracytoplasmic catalytic domain; and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages; and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor; and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- protein tyrosine phosphatase; receptor type J
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human PTPRJ. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- receptor-type tyrosine-protein phosphatase eta
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
