ASXL1 Antibody
Product Sizes
100ul
£630.00
OAGA07209-100UL
About this Product
- SKU:
- OAGA07209
- Additional Names:
- MDS; BOPS
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene is similar to the Drosophila additional sex combs gene; which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins; which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas; enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants.
- Gene Details:
- additional sex combs like 1; transcriptional regulator
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the N-terminus region of human ASXL1. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- putative Polycomb group protein ASXL1
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
