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Antibodies

FPGT Antibody

Product Sizes
100ul
£630.00
OAGA06320-100UL
About this Product
SKU:
OAGA06320
Additional Names:
GFPP
Clonality:
Polyclonal
Concentration:
0.94 mg/ml
Extra Details:
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules; such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues; such as liver and kidney; and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate; and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Gene Details:
fucose-1-phosphate guanylyltransferase
Host:
Rabbit
Immunogen:
Recombinant protein encompassing a sequence within the center region of human FPGT. The exact sequence is proprietary.
Isotype:
IgG
Protein Details:
fucose-1-phosphate guanylyltransferase
Purification:
Purified by antigen-affinity chromatography.
Shipping Conditions:
Blue Ice
Storage Conditions:
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody