ANTXR1 Antibody
Product Sizes
100ul
£630.00
OAGA05562-100UL
About this Product
- SKU:
- OAGA05562
- Additional Names:
- ATR; GAPO; TEM8
- Clonality:
- Polyclonal
- Concentration:
- 0.72 mg/ml
- Extra Details:
- This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin; the causative agent of the disease; anthrax. The binding of the protective antigen (PA) component; of the tripartite anthrax toxin; to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell; the other two components of anthrax toxin; edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.
- Gene Details:
- anthrax toxin receptor 1
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human TEM8. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- anthrax toxin receptor 1
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
