APC Antibody - C-terminal region
Product Sizes
100ul
£630.00
OAGA05270-100UL
About this Product
- SKU:
- OAGA05270
- Additional Names:
- GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion; transcriptional activation; and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP); an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
- Gene Details:
- APC; WNT signaling pathway regulator
- Host:
- Rabbit
- Immunogen:
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human APC. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- adenomatous polyposis coli protein
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
