TAGLN Antibody
Product Sizes
100ul
£630.00
OAGA04358-100UL
About this Product
- SKU:
- OAGA04358
- Additional Names:
- SM22; SMCC; TAGLN1; WS3-10; SM22-alpha
- Clonality:
- Polyclonal
- Concentration:
- Varies by lot. See vial for concentration.
- Extra Details:
- This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle; and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor; and the loss of its expression is an early event in cell transformation and the development of some tumors; coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization.
- Gene Details:
- transgelin
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human Transgelin. The exact sequence is proprietary.
- Isotype:
- IgG
- Molecular Weight:
- 23 kDa
- Protein Details:
- transgelin
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks); store at 4°C. For long-term storage; aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
