ALDH2 Antibody
Product Sizes
100ul
£630.00
OAGA04307-100UL
About this Product
- SKU:
- OAGA04307
- Additional Names:
- ALDM; ALDHI; ALDH-E2
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase; cytosolic and mitochondrial; can be distinguished by their electrophoretic mobilities; kinetic properties; and subcellular localizations. Most Caucasians have two major isozymes; while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform; which has a low Km for acetaldehydes; and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Gene Details:
- aldehyde dehydrogenase 2 family (mitochondrial)
- Host:
- Rabbit
- Immunogen:
- Recombinant protein encompassing a sequence within the center region of human ALDH2. The exact sequence is proprietary.
- Isotype:
- IgG
- Protein Details:
- aldehyde dehydrogenase; mitochondrial
- Purification:
- Purified by antigen-affinity chromatography.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
